Secukinumab - DocCheck Flexikon (2024)

FAQs

How much does secukinumab cost? ›

The list (or wholesale) price for COSENTYX, as of January 2024 is $7,408.96 a month for either a 150-mg or a 300-mg dose strength self-injection package and $4,230 per intravenous infusion. The list price may not reflect the price paid by patients; most patients with prescription coverage will pay less.

eye infection or inflammation (conjunctivitis), increased liver transaminases, and. low white blood cell count (neutropenia).

Absorption: Following a single subcutaneous dose of 150 mg or 300 mg in plaque psoriasis subjects, Cmax for secukinumab is approximately achieved after six days of administration. Steady-state concentrations of secukinumab are observed by week 24 following the 4-week dosing regimens.

Cosentyx (secukinumab) dosage forms

Psoriatic arthritis (PsA), ankylosing spondylitis (AS), and non-radiographic axial spondyloarthritis (nr-axSpA): The starting dose can be optional; if given, the typical dose is 150 mg injected under the skin (SQ) weekly for 5 weeks.

The most common reason insurers deny coverage is that other therapies were not tried prior to requesting a biologic. Other reasons for a denial of Cosentyx include how the insurer has tiered biologics or the increased number of insurance requirements listed in authorization forms.

Cosentyx is also expensive due to its innovative, highly effective biologic technology. Biologic DMARDs like Cosentyx, designed from living cells, offer targeted treatment for inflammation, but they come at a higher cost.

Initial clinical studies for IL inhibitors such as secukinumab didn't report weight gain as a side effect. Recently, other studies have reported mixed results — some show that these treatments may have no effect, while others show they may even cause weight loss.

In the few real-life studies addressing the topic of psoriatic arthritis and axial PsA, secukinumab was effective and safe in controlling disease outcomes (such as DAPSA and MDA), with survival ranging from 40% to 70% at 2 years depending on the number of prior anti-TNFAalpha-based lines of therapy [22,32].

Since its approval there have been no reports of idiosyncratic, clinically apparent liver injury attributed to secukinumab therapy. However, prospective studies have shown that secukinumab can induce reactivation of hepatitis B in persons with preexisting HBsAg or antibody to hepatitis B core antigen (anti-HBc).

It is usually given as a shot under the skin of your stomach, thigh, or upper arm to treat ankylosing spondylitis, enthesitis-related arthritis, hidradenitis suppurativa, non-radiographic axial spondyloarthritis, plaque psoriasis, or psoriatic arthritis.

How does cosentyx make you feel? ›

The most common side effects of COSENTYX include: cold symptoms, diarrhea, and upper respiratory tract infections. These are not all of the possible side effects of COSENTYX. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA.

Scapho Secukinumab Cosentyx Injection at Rs 25000/piece | Scapho Injection in Mumbai | ID: 17778263248.

Secukinumab may lower the immune system and increase the risk of infections. However, this can occur in only 1% of the patients taking the drug. A general thumb rule is not to take it with other drugs or medications that can weaken your immune system to avoid such cases. Examples would be cyclosporine or tacrolimus.

Brand names: Cosentyx

Secukinumab has an average rating of 7.2 out of 10 from a total of 109 reviews for the treatment of Plaque Psoriasis. 65% of reviewers reported a positive experience, while 24% reported a negative experience.

The cost is around £500 per injection. Has anyone been taking Cosentyx (secukinumab) injection in private dermatologists in UK?

The cost for Cosentyx (150 mg/mL) subcutaneous solution is around $7,811 for a supply of 1 milliliter(s), depending on the pharmacy you visit. Quoted prices are for cash-paying customers and are not valid with insurance plans.

The list price for ENBREL is $1,850.46 per weekly 50 mg dose. *^,† For patients with moderate to severe plaque psoriasis, the recommended dose is 50 mg twice weekly for the first 3 months followed by 50 mg weekly thereafter.